Oxidative and metabolic stability of drugs A major focus observed in recent years in drug development is to reduce the number of compound failures at a late stage. Such misfortune is frequently the result of unfavourable compound properties, like hepatic toxicity, metabolic instability or slight potency. Rational drug discovery begins with the knowledge of stability and reactivity of libraries and early prediction of properties (e.g. drug-likeness, ADME, toxicity), that influence the success of a drug candidate at the end of development. To address this challenge, Dr. I. Gatlik has invented the Electroactive Pharmaceutical Screening (EPS) System, an innovative High-Throughput Screening (HTS) solutions, to allow more informed and accurate decisions about synthesis and lead selection in the early stages. |
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Gatlik EPS
System with software and Sensor-Plate-96.2TV3 |
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